Cholecystokinin (CCK) is a digestive hormone produced primarily in the small intestine (specifically the duodenum and jejunum). It plays several important roles in digestion and appetite regulation:
Functions of Cholecystokinin
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Stimulates bile release: CCK signals the gallbladder to contract and release bile into the small intestine, which helps digest fats.
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Stimulates pancreatic enzyme secretion: It prompts the pancreas to release digestive enzymes (like lipase, amylase, and proteases) that break down fats, carbohydrates, and proteins.
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Slows gastric emptying: CCK reduces the rate at which food leaves the stomach, allowing more time for digestion in the small intestine.
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Suppresses appetite: CCK acts on the brain, particularly the hypothalamus, to promote feelings of satiety or fullness.
When is it released?
CCK is released in response to fats and proteins entering the small intestine after a meal.
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