Understanding the three-dimensional (3D) structure of proteins is crucial for deciphering their functions and developing targeted therapies for various diseases. Historically, predicting protein structures has […]
Gut taste receptors—also known as chemosensory receptors—play a surprisingly important role in regulating satiation, satisfaction, and appetite. Though we normally associate taste with the tongue […]
N-glycosylation is one of the most prevalent and complex post-translational modifications of proteins in eukaryotic cells, critically influencing protein folding, stability, trafficking, and cell-cell interactions. […]
The organisation of genes within the genome is not random but often reflects deep evolutionary pressures and developmental requirements. Among the most striking examples of […]
Monoclonal antibodies are highly specialised protein molecules that has found wide-ranging application in biotechnology and an analytical biochemistry. Of all the advances that have been […]
Topoisomerases are enzymes that play a crucial role in the maintenance and regulation of DNA structure and topology within cells. They are responsible for altering […]
The proteasome is a crucial protein complex in cells that breaks down and recycles damaged or unneeded proteins. It’s a core part of the ubiquitin-proteasome […]
Mammalian cell expression refers to the process of introducing and expressing foreign genes or proteins in mammalian cells. Mammalian cells, such as human embryonic kidney […]
Ceramides are a vital component of the skin’s barrier function and play a crucial role in maintaining healthy and hydrated skin. These lipid molecules, also […]
Milk lipoprotein lipase (LPL) is an enzyme that is present in the milk of lactating animals, including humans. It plays a crucial role in the […]
Size-exclusion chromatography (SEC), also known as gel filtration chromatography, is a widely used analytical technique in the field of biochemistry, biotechnology, and pharmaceutical sciences. It […]
Pectin methyl esterase (PME) [3.1.1.11) is an enzyme that plays a critical role in the metabolism of pectin, a complex carbohydrate that is an essential […]
The shikimate pathway is a critical metabolic pathway found in microorganisms, plants, and some fungi. It serves as the central route for the biosynthesis of […]
Lactation is one of the most remarkable physiological processes in women, providing essential nutrition and immunological protection to the newborn. The process of milk production, […]
Bradykinin is one of the plasma kinins along with kallidin. The name bradykinin is derived from the Greek word ‘bradys’ meaning slow and ‘kinein’ meaning […]
The pentose phosphate pathway is a key pathway in metabolism that is used to synthesize nucleotides NADPH and pentose sugars such as ribose-5-phosphate. It can […]
Ubiquitin, a small protein found ubiquitously in eukaryotic cells, plays a pivotal role in numerous cellular processes, ranging from protein degradation to DNA repair and […]
The p53 signaling pathway plays a crucial role in regulating apoptosis, or programmed cell death, which is essential for maintaining tissue homeostasis, eliminating damaged or […]
Gluconeogenesis is a vital metabolic pathway that allows organisms to maintain blood glucose levels during periods of fasting, starvation, or intense exercise. Derived from the […]
The urea cycle is the metabolic process by which humans remove ammonia from the body. Ammonia (NH3) is highly toxic and is the end product […]
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