Different Types of Dominance in Genetics
The concept of dominance in genetics is important in understanding why we show particular characteristics and not others. To understand dominance in genetics, let’s first […]
Biochemical Engineering
The Notch Signalling Pathway
The Notch signaling pathway is a highly conserved intercellular signaling pathway that plays a critical role in various cellular processes during development, tissue homeostasis, and […]
The Production of 3-dehydroshikimic acid by Microbial Fermentation
3-dehydroshikimic acid, also known as dehydroshikimic acid or DHS, is a chemical compound with the molecular formula C7H8O5. It belongs to the family of aromatic […]
The Use of Systems Biology in Bioprocessing
Systems biology is an interdisciplinary field that seeks to understand biological systems by integrating large-scale experimental data, computational modeling, and theoretical frameworks. It aims to […]
Affinity Tags: Benefits And Challenges
Affinity tags are short peptide sequences that are genetically fused to a target protein to facilitate its purification, detection, and sometimes, the immobilization of the […]
Cardiac Tissue Engineering
Introduction Cardiac tissue engineering represents a groundbreaking intersection of biology, engineering, and medicine, aimed at addressing the significant challenge of heart disease. As one of […]
Magnetic Mixing
Magnetic mixers are commonly used in biochemical engineering to provide efficient mixing and agitation of fluids in bioreactors, which are used to culture microorganisms or […]
Methods in Bioreactor Design
Bioreactor design is an important concern and element for the biotechnology and biochemical engineering industry. There are issues with all bioreactors that have to be […]
Employing Metabolic For The Purposes of Carbon Capture
Carbon capture is a pressing issue as the world struggles to minimise the impact of climate change. A method that has come into the reckoning […]
Mass Spectrometry – Its Use in Biotechnology
Mass spectrometry (MS) is a powerful analytical technique used to determine the mass-to-charge ratio (m/z) of ions in a sample. It is based on the […]
Process Validation in the Biotechnology Industry
Process validation is a critical aspect of ensuring the quality, safety, and efficacy of biotechnological products in the biotechnology industry. It is a systematic and […]
Lactobacillus plantarum as a Versatile Probiotic Microorganism
Lactobacillus plantarum is a prominent species within the genus Lactobacillus, a group of bacteria known for their lactic acid production and their beneficial roles in […]
Hydrophobic Chromatography
Hydrophobic chromatography or Hydrophobic Interaction Chromatography (HIC) is a separation method that relies on the hydrophobicity of the adsorbent to bind proteins which are then […]
Extracellular Vesicles and Exosomes
Extracellular vesicles (EVs) are emerging as promising new biological drug modalities. They are starting to supersede other touted technologies with considerable heft in the biotechnology […]
Exploiting Diafiltration And Ultrafiltration
Introduction To Diafiltration and Ultrafiltration Diafiltration is a membrane separation process which often forms part of a series of unit operations in downstream processing. Diafiltration […]
Multicellular Spheroids: A Three-Dimensional Marvel in Cell Culture
Introduction In the realm of cell culture, multicellular spheroids have emerged as a three-dimensional (3D) marvel, offering researchers a closer approximation of in vivo cellular […]
Flocculation
One of the fundamental processes of downstream processing of biomolecules is the separation of insoluble material from soluble material. It is regularly used in wastewater […]
Genome Clusters in the Production of Secondary Metabolites
Genomic clusters for secondary metabolites, also known as biosynthetic gene clusters (BGCs), are regions of the genome that contain genes responsible for the synthesis of […]
The Fermentation of Clavulanic Acid
The fermentation of clavulanic acid involves the cultivation of the bacterium Streptomyces clavuligerus under controlled conditions to induce the production of this important β-lactamase inhibitor. […]
The Differences Between Global and Focal Alignments in Bioinformatics
Global and local alignments are two types of sequence alignment methods used in bioinformatics. They differ in how they align two sequences and what information […]