The Bacteria: Clostridium acetobutylicum
Clostridium acetobutylicum is a well-studied, anaerobic, Gram-positive, spore-forming bacterium known for its industrial importance in biofuel and solvent production. It played a major historical role […]
Biochemical Engineering
The Role of Fermentation Media
Fermentation media, also known as culture media or growth media, play a crucial role in microbial fermentations. They provide essential nutrients and conditions necessary for […]
The Manufacture of Taxol
Taxol, also known as paclitaxel, is a complex natural product derived from the bark of the Pacific yew tree (Taxus brevifolia) and other related yew […]
Ammonium Sulphate Precipitation in Peptide Purification.
Ammonium sulfate precipitation is a widely used technique for the purification of proteins and peptides. This method exploits the differential solubility of proteins and peptides […]
The lac Operon in E. coli
The lac operon in Escherichia coli (E. coli) is a well-known example of an inducible operon. Operons are functional units of DNA that consist of […]
What is a Non-Replicative Plasmid?
A non-replicative plasmid, also known as a non-replicating plasmid or a non-replicating vector, is a type of plasmid that lacks the ability to replicate autonomously […]
Monitoring and Controlling Glycosylation in Mammalian Cell Bioprocesses
Monitoring and controlling glycosylation in mammalian cell bioprocesses is crucial for the production of biopharmaceuticals with desired glycan profiles and consistent product quality. Glycosylation refers […]
The Sequence Alignment Methods Used in Bioinformatics
In bioinformatics, there are several sequence alignment methods used to compare and align biological sequences, such as DNA, RNA, and protein sequences. Here are seven […]
Insulin Manufacture Using Gene Technology
Insulin is a vital hormone for regulating blood glucose levels. It is critical for those with Type-1 diabetes because they do not produce the hormone. […]
Genome-Scale Flux Models
Genome-scale flux models, also known as genome-scale metabolic models (GEMs) or genome-scale metabolic reconstructions, are computational representations of an organism’s metabolism at the genome scale. […]
Alginates for Gel Immobilization, Encapsulation and Scaffolds
One of the universal carbohydrate polymers used for cell immobilization is calcium alginate. This polyelectrolyte and hydrocolloid is extracted from seaweed. It has become one […]
Design of Experiments (DOE): Unlocking Insights for Optimal Decision-Making
Design of Experiments (DOE) is a systematic and efficient methodology used to plan, conduct, analyze, and interpret experiments or tests aimed at optimizing processes, products, […]
ICH Q13
ICH Q13 is a guideline that provides principles and approaches for lifecycle management of analytical procedures used in the biotechnology industry. It focuses on improving […]
Expanded Bed Chromatography
Expanded bed chromatography is one of the most recent separation techniques to come into vogue with biochemical downstream processors. It is one of a group […]
Scale-Down Models in Biotechnology: Enhancing Understanding and Optimization
Scale-down models are essential tools in biotechnology that facilitate the study of large-scale processes in smaller, more manageable settings. These models play a crucial role […]
The Bacteria: Corynebacterium glutamicum
Corynebacterium glutamicum is a Gram-positive, non-pathogenic bacterium that belongs to the genus Corynebacterium. It is widely used in industrial biotechnology for the production of various […]
The Manufacture of Factor VIII for Treating Hemophilia A
The manufacturing of factor VIII, a crucial blood clotting protein, is a complex process involving advanced biotechnological techniques. Factor VIII is primarily produced for therapeutic […]
Microcarriers in Animal Cell Cultivation
Microcarriers are an essential tool in the mass cultivation of animal cells for various applications, including biopharmaceutical production, tissue engineering, and cell-based research. These tiny […]
The Great Thing About Microalgae
Microalgae, a diverse group of microscopic photosynthetic organisms, offer a wide range of benefits across various fields, from nutrition and sustainable agriculture to environmental conservation […]
Amino-phenylboronate Activated Supports for Reversible Enzyme Immobilization
Amino-phenylboronate activated supports are a valuable tool in the field of enzyme immobilization, offering a reversible and versatile method for binding enzymes to solid matrices. […]