The Genus Rhodococcus in Biotechnology
Rhodococcus is a genus of Gram-positive, non-spore-forming bacteria that belongs to the family Nocardiaceae within the Actinobacteria phylum. These bacteria are characterized by their ability […]
Biochemical Engineering
Aspergillus niger
Aspergillus niger is a filamentous fungus belonging to the genus Aspergillus. It is one of the most common and extensively studied species of Aspergillus due […]
Monoclonal Antibodies in Biotechnology
Monoclonal antibodies are highly specialised protein molecules that has found wide-ranging application in biotechnology and an analytical biochemistry. Of all the advances that have been […]
The Role of DNA Topisomerases
Topoisomerases are enzymes that play a crucial role in the maintenance and regulation of DNA structure and topology within cells. They are responsible for altering […]
The Yeast: Candida rugosa
Candida rugosa is a yeast species belonging to the genus Candida. It is a dimorphic fungus, meaning it can exist in two different forms: yeast […]
Methanobacterium formicicum
Methanobacterium formicicum is a species of microorganism belonging to the domain of the Archaea. It is a methanogenic archaeon, meaning it produces methane as a […]
What is the difference between haploidy and monoploidy?
Haploidy and monoploidy are both terms used in genetics to describe the number of sets of chromosomes in a cell or organism. While they are […]
Plasmids – Essential In Biotechnology
Plasmids are one of the most important factors in the success of biotechnology. The word plasmid was introduced Joshua Lederberg in 1952 as the American […]
The Bacterium: Streptomyces coelicolor
Streptomyces coelicolor is a bacterium belonging to the genus Streptomyces, which is known for its ability to produce a wide range of secondary metabolites, including […]
The Process of Cell Line Development
Cell line development is a process by which the cellular machinery is used to manufacture therapeutic biologics and other proteins of interest. Introduction Tissue from […]
The Role of Post-Translational Modification in Protein Expression
Post-translational modification (PTMs) refers to a host of chemical modifications that occur on proteins after they have been synthesized from the ribosome. These modifications play […]
Mammalian Cell Expression – Why Is It So Useful in Biotechnology?
Mammalian cell expression refers to the process of introducing and expressing foreign genes or proteins in mammalian cells. Mammalian cells, such as human embryonic kidney […]
The Manufacture of L-Tryptophan using Microbial Fermentation
The manufacture of L-tryptophan, an essential amino acid, using microbial fermentation involves the utilization of microorganisms to produce and accumulate L-tryptophan through metabolic pathways and […]
Using Microbial Fermentation to Produce Pyruvate
Microbial fermentation is a metabolic process employed by microorganisms to convert organic compounds into simpler molecules, such as pyruvate. Pyruvate is a key intermediate in […]
Design For Different Types Of Fermentation
When we think about fermentation design we are considering what the properties are that makes for the ideal fermenter. Fermentation is primarily about supporting growth of […]
What is the unfolded protein response (UPR) in biological cells?
The unfolded protein response (UPR) is a cellular stress response mechanism that is activated when the endoplasmic reticulum (ER) in a cell is overwhelmed by […]
Size-Exclusion Chromatography
Size-exclusion chromatography (SEC), also known as gel filtration chromatography, is a widely used analytical technique in the field of biochemistry, biotechnology, and pharmaceutical sciences. It […]
Why Rhodotorula toruloides is the Next Bio-oil Producing Microorganism
Rhodotorula toruloides is a yeast species that has gained increasing attention as a bio-oil producing microorganism in recent years. Bio-oil, also known as pyrolysis oil […]
Bacteriolytic Enzymes Are Promising Alternatives to Antibiotics
Bacteriolytic enzymes, such as lysostaphin, have been proposed as potential alternatives to antibiotics for the treatment of bacterial infections. These enzymes work by breaking down […]
Nanofiltration In Bioprocessing
Nanofiltration (NF) is a membrane separation technology that is used extensively in biochemical engineering for the separation, purification, and concentration of biomolecules and other compounds. […]