Pseudomonas aeruginosa

Pseudomonas aeruginosa is commonly associated with food contamination and causes infection in immunocompromised people. It is the agent responsible for ventilator induced pneumonia. The bacteria, once established is extremely difficult to get rid of.

It also causes skin infections especially follicule infection. Pseudomonas aeruginosa folliculitis (PF) can sometimes develop after exposure to contaminated water in heated swimming pools, whirlpools, and hot-tubes, or after diving suit dressing. It is often the cause of swimmers acne.

P. aeruginosa is a Gram -ve bacteria. It is also described as strictly aerobic, oxidase-positive, non-sporulating, motile and lactose non-fermenting bacillus. It produces water-soluble fluorescent pigments evident when the organism is isolated on culture media

Pseudomonas produced biofilms to protect itself from degradation and as a physical barrier to damage from bacteriocins. Virulence factors include   such as pyocyanin, protease, and rhamnolipid.

It should be absent in cosmetic samples and is tested for as part of microbiological specifications. 

Inhibition

Various Lactobacilli including Pediococcus produce bacteriocins that inhibit biofilm formation and stop it from producing other virulence factors.

References

Lee, D. H., Kim, B. S., & Kang, S. S. (2020). Bacteriocin of Pediococcus acidilactici HW01 inhibits biofilm formation and virulence factor production by Pseudomonas aeruginosa. Probiotics and antimicrobial proteins12(1), pp. 73-81.

Rai, S., Yadav, U. N., Pant, N. D., Yakha, J. K., Tripathi, P. P., Poudel, A., & Lekhak, B. (2017). Bacteriological profile and antimicrobial susceptibility patterns of bacteria isolated from pus/wound swab samples from children attending a tertiary care hospital in Kathmandu, Nepal. International journal of microbiology2017.

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