Attenuation in Genetic Control of Gene Transcription
Attenuation is a regulatory mechanism in prokaryotes that controls gene expression at the level of transcription elongation, rather than initiation (Fincham, 1983). It is a […]
Biotechnology
The Importance Of The Copy Number In Biotechnology
Copy number in genetics refers to the number of copies of a particular DNA sequence—most commonly a gene or genomic region—present in a cell’s genome. […]
A Key Compound, 5-aminolevulinic acid (ALA) In Biochemistry
5-Aminolevulinic acid (5-ALA, often abbreviated simply as ALA) occupies a distinctive position at the intersection of fundamental biochemistry and applied biotechnology. It is a small, […]
Disulphide Cross-Linking in Proteins: Mechanisms, Biological Significance, and Biotechnological Applications
Proteins are the primary functional molecules of the cell, carrying out structural, catalytic, regulatory, and signaling roles. While the amino acid sequence encoded by DNA […]
Lean Manufacturing In The Biotechnology Industry
Lean manufacturing can be highly effective in biotechnology, but it must be adapted to the unique constraints of biological systems, strict regulatory oversight, and complex […]
The Global Transcriptional Regulators
Global transcriptional regulators are high-level regulatory proteins (usually transcription factors) that control the expression of large sets of genes across multiple pathways. Instead of regulating […]
Monoliths as Adsorbents in Chromatography
Chromatography is one of the most important analytical and preparative techniques in chemistry, biotechnology, and materials science. Traditionally, chromatographic separations rely on packed beds of […]
The glutamine synthetase (GS) expression system
The glutamine synthetase (GS) expression system is one of the most widely used and industrially proven platforms for the development of Chinese hamster ovary (CHO) […]
Is The Loss of Attenuation of Intracellular Signalling Responsible for Cancer?
Cancer has long been understood as a disease of dysregulated cell growth, survival, and proliferation. While multiple paradigms exist to explain the complex processes that […]
The Manufacture of Lactoferrin
The manufacture and purification of lactoferrin (LF), a multifunctional iron-binding glycoprotein primarily found in milk, involves several carefully controlled steps to ensure purity, bioactivity, and […]
Bacillus clausii: A Resilient Probiotic with Diverse Applications
Bacillus clausii is a Gram-positive, rod-shaped, spore-forming bacterium widely recognized for its probiotic properties. Originally isolated from soil, it has gained significant attention in clinical, […]
Combinatorial Gene Control
Combinatorial gene control refers to the regulation of gene expression by the coordinated action of multiple gene regulatory proteins, such as transcription factors and co-regulators, […]
Deep Learning for Sequence-to-Expression Models in Strain Optimization
Deep learning is a subset of machine learning that uses neural networks with multiple layers i.e. deep neural networks, to learn complex patterns from large […]
Nanobubble Creation for Nutraceutical Delivery In Beverages
Nanobubbles offer tremendous variety, novelty and functional benefits in the delivery of nutraceuticals. They are already showing promise with drug delivery especially in the pharmaceutical […]
Spider Silk Proteins Through Precision Fermentation
Spider silk proteins are truly fascinating, and they represent a cutting-edge development in biomaterials and sustainability. Here’s everything you need to know about them: What […]
Gene Duplication
Gene duplication is a significant evolutionary event where a segment of DNA, including one or more genes, is copied and inserted into the genome. This […]
Medical Devices
What Counts as a Medical Device A medical device is broadly defined as any instrument, apparatus, implant, software, material, or other article intended by the […]
Baculoviruses in Biotechnology
Baculoviruses, a family of large DNA viruses primarily infecting insects, have emerged as valuable tools in biotechnology with diverse applications. Among these, the Autographa californica […]
The Role of Digital Twins in Biotechnology
Digital twins in biotechnology refer to virtual replicas or models of biological entities, systems, or processes that are created using digital technologies. They are a […]
Plasmids – Essential In Biotechnology
Plasmids are one of the most important factors in the success of biotechnology. The word plasmid was introduced by Joshua Lederberg in 1952 as the […]