Recombineering in Biotechnology
Precise manipulation of genetic material is a central requirement of modern biotechnology, underpinning advances in functional genomics, metabolic engineering, and synthetic biology. Early molecular cloning […]
Biotechnology
Finding Value In Chinese Distillers Grains (CDG)
Chinese distillers grains, commonly referred to in technical and commercial contexts as Chinese distillers dried grains (CDG) with solubles (DDGS) or, more broadly, distillers grains […]
What are the data challenges in biotechnology that compromise the use of artificial intelligence?
AI has enormous potential in biotechnology, but its use is still incomplete because of several persistent data-related challenges. These challenges span data availability, quality, structure, […]
Colorectal Cancer
Colorectal cancer (CRC) is one of the most common malignancies worldwide and a leading cause of cancer-related morbidity and mortality. It encompasses cancers arising in […]
The siRNA-based Drugs
Small interfering RNA (siRNA)–based therapeutics represent one of the most mature clinical applications of RNA interference (RNAi), a conserved cellular mechanism for sequence-specific gene silencing. […]
Developing AAV1-hOTOF Gene Therapy for Autosomal Recessive Deafness 9
AAV1-hOTOF gene therapy is an experimental molecular treatment developed for Autosomal Recessive Deafness 9 (DFNB9), a form of congenital, prelingual, severe-to-profound hearing loss caused by […]
Protein Secretion In E.coli
Protein secretion in Escherichia coli is a fundamental cellular process that enables proteins to reach their correct cellular or extracellular destinations. As a Gram-negative bacterium, […]
Attenuation in Genetic Control of Gene Transcription
Attenuation is a regulatory mechanism in prokaryotes that controls gene expression at the level of transcription elongation, rather than initiation (Fincham, 1983). It is a […]
The Importance Of The Copy Number In Biotechnology
Copy number in genetics refers to the number of copies of a particular DNA sequence—most commonly a gene or genomic region—present in a cell’s genome. […]
Burkholderia cepacia complex (BCC)
Burkholderia cepacia (aka Pseudomonas cepacia) is a Gram-negative, aerobic, non-fermenting bacillus that is clinically important as an opportunistic pathogen, particularly in patients with cystic fibrosis […]
Tumour-Specific Immunogene Therapy
Tumour-specific immunogene therapy represents an emerging therapeutic paradigm that integrates gene therapy, immunotherapy, and targeted protein delivery to overcome longstanding limitations in the treatment of […]
Disulphide Cross-Linking in Proteins: Mechanisms, Biological Significance, and Biotechnological Applications
Proteins are the primary functional molecules of the cell, carrying out structural, catalytic, regulatory, and signaling roles. While the amino acid sequence encoded by DNA […]
The Production of D-Limonene
1. What is D-Limonene? D-Limonene is a naturally occurring monocyclic monoterpene hydrocarbon (C₁₀H₁₆). It is optically active; the D-enantiomer is responsible for the characteristic citrus […]
Gene Silencing
Gene silencing is a fundamental biological phenomenon through which cells regulate gene expression by preventing specific genes from being transcribed into RNA or translated into […]
Lean Manufacturing In The Biotechnology Industry
Lean manufacturing can be highly effective in biotechnology, but it must be adapted to the unique constraints of biological systems, strict regulatory oversight, and complex […]
What Are Nitazenes and Why Are They Considered More Addictive or Dangerous Than Fentanyl?
What Are Nitazenes? Nitazenes are a family of synthetic opioids originally created in the 1950s during pharmaceutical research. They were never approved for medical use […]
The Global Transcriptional Regulators
Global transcriptional regulators are high-level regulatory proteins (usually transcription factors) that control the expression of large sets of genes across multiple pathways. Instead of regulating […]
The Chikungunya virus (CHIKV)
Chikungunya virus (CHIKV) is an arthropod-borne virus belonging to the genus Alphavirus within the family Togaviridae. It is transmitted primarily through the bites of infected […]
Monoliths as Adsorbents in Chromatography
Chromatography is one of the most important analytical and preparative techniques in chemistry, biotechnology, and materials science. Traditionally, chromatographic separations rely on packed beds of […]
Bacillus circulans
Bacillus circulans is a species of bacteria belonging to the genus Bacillus. Classification: Kingdom: Bacteria Phylum: Firmicutes Class: Bacilli Order: Bacillales Family: Bacillaceae Genus: Bacillus […]