Natural Antifreeze Phenomena in Biological Cells
Natural antifreeze mechanisms in biological cells enable certain organisms to survive and thrive in extremely low-temperature environments. These adaptations are particularly crucial in polar and […]
Biochemistry
Exploiting Fluorescence Microscopy
Fluorescence microscopy is a powerful imaging technique widely used in biology, medicine, and materials science to study the structure and function of cells, tissues, and […]
Umami – The 5th Taste
Umami flavour makes for a fascinating story because of the molecular nature of this sensory sensation. For many years, it was thought to be an […]
Protein Refolding
Protein refolding refers to the process of restoring the three-dimensional shape of a protein that has been unfolded or denatured. Proteins are large molecules that […]
What are Fats?
Fats, also known as triglycerides, are a type of lipid and an important energy storage molecule in many organisms. They are composed of glycerol and […]
Bacteriophages
Bacteriophages, often referred to as phages, are viruses that specifically infect and replicate within bacteria. The term “bacteriophage” originates from the Greek words “bakterion,” meaning […]
Beta-lactoglobulin
Beta-lactoglobulin (BLG) is a major whey protein found in the milk of mammals, particularly in cow’s milk. It belongs to the lipocalin protein family and […]
Polyketide Synthesis
Polyketide synthesis is a fascinating process, mainly occurring in microorganisms like bacteria and fungi, which produces a diverse group of secondary metabolites known as polyketides. […]
The Transient Receptor Potential Vanilloid 1 (TRPV1) Receptor
Introduction to TRPV1 The Transient Receptor Potential Vanilloid 1 (TRPV1) receptor, also known as the capsaicin receptor, is a member of the TRP (transient receptor […]
How do Cells Stick Together? Adhesion Proteins Of Course
Adhesion proteins play a fundamental role in various biological processes by facilitating cell-cell and cell-extracellular matrix (ECM) interactions. These proteins are crucial for maintaining tissue […]
Decoding Protein Function: Genetic Active Site Search (GASS) as a Tool for Identifying Binding Sites
Understanding the function of proteins is paramount in elucidating biological processes and developing targeted therapeutics. An essential aspect of protein function is the identification of […]
Revolutionizing Protein Structure Prediction with AlphaFold2
Understanding the three-dimensional (3D) structure of proteins is crucial for deciphering their functions and developing targeted therapies for various diseases. Historically, predicting protein structures has […]
Monoclonal Antibodies in Biotechnology
Monoclonal antibodies are highly specialised protein molecules that has found wide-ranging application in biotechnology and an analytical biochemistry. Of all the advances that have been […]
The Role of DNA Topisomerases
Topoisomerases are enzymes that play a crucial role in the maintenance and regulation of DNA structure and topology within cells. They are responsible for altering […]
Mammalian Cell Expression – Why Is It So Useful in Biotechnology?
Mammalian cell expression refers to the process of introducing and expressing foreign genes or proteins in mammalian cells. Mammalian cells, such as human embryonic kidney […]
Ceramides Are Interesting!
Ceramides are a vital component of the skin’s barrier function and play a crucial role in maintaining healthy and hydrated skin. These lipid molecules, also […]
What is Milk Lipoprotein Lipase?
Milk lipoprotein lipase (LPL) is an enzyme that is present in the milk of lactating animals, including humans. It plays a crucial role in the […]
Size-Exclusion Chromatography
Size-exclusion chromatography (SEC), also known as gel filtration chromatography, is a widely used analytical technique in the field of biochemistry, biotechnology, and pharmaceutical sciences. It […]
Pectin methyl esterase (PME)
Pectin methyl esterase (PME) [3.1.1.11) is an enzyme that plays a critical role in the metabolism of pectin, a complex carbohydrate that is an essential […]
The Shikimate Pathway
The shikimate pathway is a critical metabolic pathway found in microorganisms, plants, and some fungi. It serves as the central route for the biosynthesis of […]